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What is CBD?
CBD Cannabidiol is one of over one-hundred cannabinoids found in both variations of the Cannabis plant (Hemp and Marijuana.) Cannabinoids are various (over 100) chemical compounds present in the material of the Cannabis plant. Unlike its cousin THC, CBD does not cause you to feel a “high” or an impaired feeling when consumed. They are both psychoactive, in the same way as caffeine, in that they can affect your mind or mood
What is CBN?
CBN Cannabinol is an extremely rare cannabinoid found in very small quantities in the Cannabis plant as CBN is a byproduct of the breakdown of THC. Don’t worry though as CBN is non-psychoactive and will not cause you to feel high. While the study of CBN is still in its infancy, there have been promising results.
The cannabis plant has been used throughout human history for its medicinal properties. The first recorded uses of Cannabis as a drug date back to 2700 BC in China where it was called, “The drug that takes away the mind,” they also used it to treat neurological disorders and blood clots.
- The ancient Greeks used the plant to treat wounds.
- The Vikings used it to soothe toothaches.
- Queen Elizabeth I used it to quell her menstrual cramps.
- In the 19th and 20th Centuries, cannabis was included in hundreds of medicines.
Its study however has only truly recently begun. It has only been since 1992 that Lumir Hanus, a Czech researcher working at the Hebrew University of Jerusalem, discovered the Endocannabinoid System. There are currently a number of studies under way to research any potential benefit of CBD. In 2018 the Food and Drug Administration approved a prescription CBD to treat seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome, or tuberous scierosis complex (TSC). It is the only use approved by the Food and Drug Administration to date.
How does it Work?
CBD works alongside the human body utilizing what is known as THE ENDOCANNABINOID SYSTEM or ECS. The ECS consists of receptors in your body and brain that cannabinoids are able to attach to. That’s right! Your body has a highway built just for cannabinoids. Why you ask? Because our bodies naturally produce things called endocannabinoids similar to cannabinoids found in the cannabis plant!
CB1 and CB2 Receptors
Receptors are typically found in your brain and central nervous system THC tends to gravitate towards these receptors and they are what allows THC to produce its various psychoactive effects CB2 Receptors, on the other hand, are typically found more in the peripheral nervous system and organs that are typically associated with our immune system. CBD does not naturally bond to either of the receptors, instead it acts as a reuptake inhibitor protecting our body’s endogenous cannabinoids from destruction. According to a team of Stony Brook University scientists, CBD functions as an anandamide reuptake and breakdown inhibitor, thereby raising endocannabinoid levels in the brain’s synapses. By delaying the reuptake of this neurotransmitter, CBD boosts adenosine levels in the brain, which regulates adenosine receptor activity. A1A and A2A adenosine receptors play significant roles in cardiovascular function, regulating myocardial oxygen consumption and coronary blood flow.